Conditional copula models for correlated survival endpoints: Individual patient data meta-analysis of randomized controlled trials.
Sign Up to like & getrecommendations! Published in 2021 at "Statistical methods in medical research"
DOI: 10.1177/09622802211046390
Abstract: Correlations among survival endpoints are important for exploring surrogate endpoints of the true endpoint. With a valid surrogate endpoint tightly correlated with the true endpoint, the efficacy of a new drug/treatment can be measurable on… read more here.
Keywords: patient data; treatment; survival endpoints; meta ... See more keywords
Reduction in number to treat versus number needed to treat
Sign Up to like & getrecommendations! Published in 2021 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-021-01246-5
Abstract: Background We propose a new measure of treatment effect based on the expected reduction in the number of patients to treat (RNT) which is defined as the difference of the reciprocals of clinical measures of… read more here.
Keywords: treat; survival endpoints; number; reduction number ... See more keywords