Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.03.011
Abstract: Sirtuins (SIRTs) 1 and 2 deacetylases are overexpressed in hepatocellular carcinoma (HCC) and are associated with tumoral progression and multidrug resistance (MDR). In this study we analyzed whether SIRTs 1 and 2 activities blockage was… read more here.
Keywords: survival migration; hepatocellular carcinoma; migration; mrp3 ... See more keywords
Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Oncogenesis"
DOI: 10.1038/s41389-020-0243-y
Abstract: High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. New evidence supports a hypothesis that HGSOC can originate from fallopian tube epithelium (FTE). It is unclear how genetic alterations and pathophysiological processes drive… read more here.
Keywords: survival migration; migration attachment; fallopian tube; tumor precursors ... See more keywords
The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14213
Abstract: Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence receptor, because it promotes… read more here.
Keywords: survival migration; cell survival; migration; cell death ... See more keywords
Ceria Nanoparticles Decrease UVA-Induced Fibroblast Death Through Cell Redox Regulation Leading to Cell Survival, Migration and Proliferation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.577557
Abstract: Exposure to ultraviolet radiation is a major contributor to premature skin aging and carcinogenesis, which is mainly driven by overproduction of reactive oxygen species (ROS). There is growing interest for research on new strategies that… read more here.
Keywords: survival migration; uva induced; cell survival; proliferation ... See more keywords
Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14246247
Abstract: Uveal melanoma (UM) originating in the eye and metastasizing to the liver is associated with poor prognosis and has only one approved therapeutic option. We hypothesized that liver-borne growth factors may contribute to UM growth.… read more here.
Keywords: growth; tumor growth; survival migration; uveal melanoma ... See more keywords