Prospective trial to evaluate the prognostic value of different nutritional assessment scores for survival in pancreatic cancer surgery
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Surgery"
DOI: 10.1093/bjs/znab202.029
Abstract: Malnutrition is associated with poor survival in pancreatic cancer patients. Nutritional scores show great heterogeneity diagnosing malnutrition. The aim of this study was to find the score best suitable to identify patients with malnutrition related… read more here.
Keywords: survival pancreatic; assessment; malnutrition; risk ... See more keywords
Abstract PO-030: Deep-learning image-based tumor, stroma, and lymphocytes spatial relationships and clinicopathological features that affect survival in pancreatic cancer patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.panca20-po-030
Abstract: Background: Stromal and lymphocyte density have each been implicated in differential survival in pancreatic cancer (Torphy, 2018 & Orhan, 2020). In this study, we developed an automated deep-learning system to provide risk-assessment upon spatial relationships… read more here.
Keywords: spatial relationships; survival pancreatic; deep learning; pancreatic cancer ... See more keywords
MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming
Sign Up to like & getrecommendations! Published in 2023 at "EMBO reports"
DOI: 10.15252/embr.202255643
Abstract: Extensive desmoplasia and poor vasculature renders pancreatic tumors severely hypoxic, contributing to their aggressiveness and therapy resistance. Here, we identify the HuR/MYB/HIF1α axis as a critical regulator of the metabolic plasticity and hypoxic survival of… read more here.
Keywords: pancreatic cancer; hypoxic survival; myb; survival pancreatic ... See more keywords
Leptin involvement in the survival of pancreatic adenocarcinoma patients with obesity and diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202202_28127
Abstract: OBJECTIVE Current molecular characterization of pancreatic ductal adenocarcinoma (PDAC) does not incorporate the host reaction to cancer cells and cannot predict the response to chemo- or immunotherapy. Leptin is an adipokine involved in regulating energy… read more here.
Keywords: survival; leptin involvement; involvement survival; survival pancreatic ... See more keywords