Restricted Mean Survival Time Analysis to Estimate SGLT2i–Associated Heterogeneous Treatment Effects on Primary and Secondary Prevention of Cardiorenal Outcomes in Patients With Type 2 Diabetes in Taiwan
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.46928
Abstract: Key Points Question Is restricted mean survival time (RMST) analysis feasible to translate comparative cardiovascular and kidney outcomes of sodium-glucose cotransporter-2 inhibitor (SGLT2i) vs dipeptidyl peptidase-4 inhibitor (DPP4i) therapy in routine clinical settings? Findings In… read more here.
Keywords: cardiorenal outcomes; restricted mean; analysis; mean survival ... See more keywords
A nonparametric simultaneous confidence band for biomarker effect on the restricted mean survival time
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9618
Abstract: Study of prognostic and predictive biomarkers plays an important role in the design and analysis of clinical trials. The Cox proportional hazards model is often used to study the biomarker main effect and the treatment‐biomarker… read more here.
Keywords: effect; biomarker; restricted mean; mean survival ... See more keywords
Nonparametric estimation of marked survival data in the presence of dependent censoring
Sign Up to like & getrecommendations! Published in 2023 at "Statistics in Medicine"
DOI: 10.1002/sim.9710
Abstract: We consider nonparametrically estimating the joint distribution of a survival time and mark variable, where the survival time is subject to right censoring and the mark variable is only observed when the survival time is… read more here.
Keywords: estimation marked; survival data; marked survival; dependent censoring ... See more keywords
Designing superiority trials with window mean survival time as a primary endpoint.
Sign Up to like & getrecommendations! Published in 2023 at "Statistics in medicine"
DOI: 10.1002/sim.9738
Abstract: Window mean survival time (WMST), a simple extension of restricted mean survival time (RMST), allows for clinicians to evaluate the mean survival difference between treatment groups in specific windows of time during the follow-up period… read more here.
Keywords: time; primary endpoint; mean survival; window mean ... See more keywords
The Restricted Mean Survival Time as a Tool for Ranking Comparative Outcomes in a Narrative Review that Evaluates a Network of Randomized Trials: An Example Based on PCSK9 Inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Cardiovascular Drugs"
DOI: 10.1007/s40256-020-00444-8
Abstract: Introduction On the basis of two randomized trials, evolocumab and alirocumab have been approved in patients with cardiovascular disease. The evidence on these two agents has been studied through different methods of analysis that span… read more here.
Keywords: survival time; network; narrative review; restricted mean ... See more keywords
Inflammatory markers as prognostic factors in metastatic castration-resistant prostate cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Actas urologicas espanolas"
DOI: 10.1016/j.acuro.2020.08.001
Abstract: INTRODUCTION Inflammatory markers have prognostic value in various tumors due to the role of inflammatory phenomena at different stages of tumor development. The aim of this study is to demonstrate the prognostic value of these… read more here.
Keywords: markers prognostic; inflammatory markers; survival time; metastatic castration ... See more keywords
Rural LVAD Recipients Experience Similar Survival and Transplant Times Compared to Urban Counterparts
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2018.07.421
Abstract: Introduction Despite the tendency for rural individuals with advanced heart failure (HF) to experience poor outcomes compared to urban counterparts, little is known about how rurality may impact survival and time to transplant for recipients… read more here.
Keywords: lvad recipients; survival time; time; transplant ... See more keywords
Integration of RNA-Seq and RPPA data for survival time prediction in cancer patients
Sign Up to like & getrecommendations! Published in 2017 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2017.08.028
Abstract: Integration of several types of patient data in a computational framework can accelerate the identification of more reliable biomarkers, especially for prognostic purposes. This study aims to identify biomarkers that can successfully predict the potential… read more here.
Keywords: survival time; time prediction; integration; time ... See more keywords
Histologic and radiological analysis on bone fractures: Estimation of posttraumatic survival time in skeletal trauma.
Sign Up to like & getrecommendations! Published in 2019 at "Forensic science international"
DOI: 10.1016/j.forsciint.2019.109909
Abstract: In antemortem fractures, the estimation of the amount of time that has lapsed between the traumatic event and eventual death (the socalled 'posttraumatic survival time' or PTST) can have substantial implications in legal proceedings. It… read more here.
Keywords: survival time; fractures estimation; radiology; posttraumatic survival ... See more keywords
The Survival Time of Restorations Is Shortened in Patients with Dry Mouth.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of dentistry"
DOI: 10.1016/j.jdent.2021.103794
Abstract: OBJECTIVES The aim of this retrospective data collection study was to determine the effect size of dry mouth on the survival of restorations and teeth. METHODS The data were collected from the electronic patient files… read more here.
Keywords: survival time; mouth patients; mouth; patients dry ... See more keywords
Differential mRNA expression combined with network pharmacology reveals network effects of Liangxue Tongyu Prescription for acute intracerebral hemorrhagic rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112231
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Liangxue Tongyu Prescription (LTP) is a traditional Chinese medicine formula composed of 8 crude drugs that is widely used to treat acute intracerebral hemorrhage (AICH). AIM OF THE STUDY To verify the efficacy… read more here.
Keywords: survival time; network; pharmacology; model ... See more keywords