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   Articles with "survivin" as a keyword



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Selective Disruption of Survivin's Protein‐Protein Interactions: A Supramolecular Approach Based on Guanidiniocarbonylpyrrole

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recommendations! Published in 2022 at "Chembiochem"

DOI: 10.1002/cbic.202100618

Abstract: Targeting specific protein binding sites to interfere with protein‐protein interactions (PPIs) is crucial for the rational modulation of biologically relevant processes. Survivin, which is highly overexpressed in most cancer cells and considered to be a… read more here.

Keywords: protein protein; selective disruption; disruption survivin; protein interactions ... See more keywords
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Dihydromyricetin suppresses tumor growth via downregulation of the EGFR/Akt/survivin signaling pathway.

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recommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23328

Abstract: Deregulation of epidermal growth factor receptor (EGFR) signaling is frequently observed in non‐small cell lung cancer (NSCLC). The present study aimed to determine the impact of dihydromyricetin (DHM) on NSCLC, a natural compound extracted from… read more here.

Keywords: egfr akt; growth; dhm; present study ... See more keywords
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Survivin a pivotal antiapoptotic protein in rheumatoid arthritis

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28784

Abstract: Rheumatoid arthritis (RA) is an autoimmune disease, pathologically characterized by lymphocyte infiltration of the synovial membrane that leads to chronic inflammation and progressive joint damage. RA develops as a result of increased cell infiltration and… read more here.

Keywords: protein; survivin; antiapoptotic protein; rheumatoid arthritis ... See more keywords
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Resina Draconis extract exerts anti‐HCC effects through METTL3‐m6A‐Survivin axis

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7467

Abstract: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. Herbal medicines have become an important treasure reservoir for anti‐HCC drugs because of their high efficiency and low toxicity. Herein, we investigated whether… read more here.

Keywords: resina draconis; hcc; mettl3 m6a; survivin ... See more keywords
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The protection effects of survivin in the cell model of CVB3-induced viral myocarditis

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recommendations! Published in 2020 at "Heart and Vessels"

DOI: 10.1007/s00380-020-01607-y

Abstract: Viral myocarditis (VMC) is a widely studied but poorly understood inflammatory cardiomyopathy which mainly affects children and young adults and results in adverse outcomes. Cardiomyocyte apoptosis was reported important in the progress of coxsackievirus B3… read more here.

Keywords: caspase; cvb3 induced; survivin; cell model ... See more keywords
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p53 expression and subcellular survivin localization improve the diagnosis and prognosis of patients with diffuse astrocytic tumors

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recommendations! Published in 2017 at "Cellular Oncology"

DOI: 10.1007/s13402-017-0361-5

Abstract: PurposeDiffuse astrocytic tumors are the most frequently occurring primary central nervous system (CNS) tumors. Their histological sub-classification into diffuse astrocytoma (DA), anaplastic astrocytoma (AA) and glioblastoma (GB) is challenging and the available prognostic factors are… read more here.

Keywords: diffuse astrocytic; survivin; expression; p53 expression ... See more keywords
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Chloroquine in combination with aptamer-modified nanocomplexes for tumor vessel normalization and efficient erlotinib/Survivin shRNA co-delivery to overcome drug resistance in EGFR-mutated non-small cell lung cancer.

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recommendations! Published in 2018 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2018.06.034

Abstract: Although novel molecular targeted drugs have been recognized as an effective therapy for non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) activating mutations, their efficacy fails to meet the expectation due to… read more here.

Keywords: survivin; delivery; drug; resistance ... See more keywords
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Survivin in autoimmune diseases.

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recommendations! Published in 2017 at "Autoimmunity reviews"

DOI: 10.1016/j.autrev.2017.05.016

Abstract: Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-RNA biogenesis. It is an established marker of malignant cell transformation. In non-malignant conditions, the unique properties of survivin make it indispensable… read more here.

Keywords: survivin autoimmune; survivin; autoimmune diseases; pathology ... See more keywords
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HSP90 inhibitor NVP-AUY922 induces cell apoptosis by disruption of the survivin in papillary thyroid carcinoma cells.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.04.056

Abstract: Heat shock protein 90 (HSP90) is a molecular chaperone required for maintaining the stability and function of signal proteins that plays an important role in promoting the growth and survival of cancer cells. The incidence… read more here.

Keywords: papillary thyroid; survivin; auy922; cell apoptosis ... See more keywords
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ROS modifiers and NOX4 affect the expression of the survivin‐associated radio‐adaptive response

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recommendations! Published in 2018 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2018.04.547

Abstract: Abstract The survivin‐associated radio‐adaptive response can be induced following exposure to ionizing radiation in the dose range from 5 to 100 mGy, and its magnitude of expression is dependent upon the TP53 mutational status of… read more here.

Keywords: response; survivin; adaptive response; tp53 mut ... See more keywords

Co-delivery of paclitaxel and anti-survivin siRNA via redox-sensitive oligopeptide liposomes for the synergistic treatment of breast cancer and metastasis.

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recommendations! Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.06.071

Abstract: The overexpression of survivin in breast cancer cells is an important factor of paclitaxel (PTX) resistance in breast cancer. To overcome PTX resistance and improve the antitumor effect of PTX, we developed a novel liposome-based… read more here.

Keywords: survivin; ptx; sirna; breast cancer ... See more keywords