Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients
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DOI: 10.1002/cam4.2773
Abstract: Survivin is an inhibitor of apoptosis. Aberrant survivin expression occurs in malignant tumors and has often been linked to unfavorable patient outcome. Here we analyzed 12 432 prostate cancers by immunohistochemistry. Survivin immunostaining was regularly… read more here.
Keywords: prostate; prognosis; expression; survivin expression ... See more keywords
High nuclear Survivin expression as a poor prognostic marker in pancreatic ductal adenocarcinoma
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DOI: 10.1002/jso.25253
Abstract: Survivin, one of the key regulators of mitosis and apoptosis, has long been well recognized to play important biological roles in many neoplasms, including pancreatic ductal adenocarcinoma (PDAC). However, its prognostic value in PDAC remains… read more here.
Keywords: expression poor; high nuclear; pancreatic ductal; ductal adenocarcinoma ... See more keywords
Expression of antiapoptotic proteins livin and survivin in pediatric AML patients, as prognostic markers
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DOI: 10.1080/08880018.2018.1530702
Abstract: Abstract Objective: Survivin and livin are highly expressed in various malignancies and their expression levels may be related to unfavorable prognosis. The aim was to investigate the relationships of these two markers with some prognostic… read more here.
Keywords: aml patients; livin survivin; expression; showed significant ... See more keywords
Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells
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DOI: 10.1111/jcmm.16135
Abstract: Dysfunction of epidermal growth factor receptor (EGFR) signalling plays a critical role in the oncogenesis of non–small‐cell lung cancer (NSCLC). Here, we reported the natural product, licochalcone A, exhibited a profound anti‐tumour efficacy through directly… read more here.
Keywords: licochalcone; egfr signalling; nsclc cells; cancer ... See more keywords
Survivin expression pattern in the intestine of normoxic and ischemic rats
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DOI: 10.1186/s12876-017-0625-6
Abstract: BackgroundSurvivin, a member of the inhibitor of apoptosis protein (IAP) family, regulates mitosis and chromosome segregation. The expression of survivin proceeds during embryonic development and in addition has already been demonstrated in cancer cells. However,… read more here.
Keywords: intestine; small intestinal; tissue; expression ... See more keywords
The prognostic significance of survivin expression in patients with HNSCC: a systematic review and meta-analysis
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DOI: 10.1186/s12885-021-08170-3
Abstract: Background Survivin has been recently identified as a promising novel therapeutic target and prognostic marker in different types of cancer. Here we conducted a comprehensive meta-analysis to better clarify they the precise prognostic and diagnostic… read more here.
Keywords: survivin expression; analysis; hnscc; meta analysis ... See more keywords
Micropapillary Structures in Colorectal Cancer: An Anoikis-resistant Subpopulation.
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DOI: 10.21873/anticanres.12539
Abstract: BACKGROUND/AIM Micropapillary structures (MIPs) are focal piles of columnar cells without extracellular matrix contact, and common in serrated colorectal carcinoma (CRC). In order to characterize biology of MIPs in colorectal cancer (CRC), the proliferation and… read more here.
Keywords: colorectal cancer; micropapillary structures; subpopulation; cancer ... See more keywords
P53 and survivin expression in renal cell carcinoma
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DOI: 10.4103/ua.ua_91_22
Abstract: Objective: Mutation of p53 is detected in more than 50% of human cancers, expression of p53 has a potential prognostic value in patients with renal cell carcinoma (RCC). Survivin is a member of the inhibitor… read more here.
Keywords: cell; p53 survivin; expression; p53 ... See more keywords
Clinicopathologic Significance of Survivin Expression in Relation to CD133 Expression in Surgically Resected Stage II or III Colorectal Cancer
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DOI: 10.4132/jptm.2016.09.23
Abstract: Background Cancer stem cells have been investigated as new targets for colorectal cancer (CRC) treatment. We recently reported that CD133+ colon cancer cells showed chemoresistance to 5-fluorouracil through increased survivin expression and proposed the survivin… read more here.
Keywords: survivin expression; cd133; expression; cancer ... See more keywords