Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.28
Abstract: The DENND1A has been identified as a guanine nucleotide exchange factor for small GTPase Rab35, which functions in endocytic trafficking to mediate the recycling of selective cargos. Genetic alterations within the DENND1A gene have been… read more here.
Keywords: dennd1a susceptibility; ovary syndrome; polycystic ovary; susceptibility gene ... See more keywords
A multisite SNP genotyping and macrolide susceptibility gene method for Mycoplasmapneumoniae based on MALDI-TOF MS
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102447
Abstract: Summary In this study, a multisite SNP genotyping and macrolide (ML) susceptibility gene test method for Mycoplasma pneumoniae (M. pneumoniae) was developed based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The detection limit… read more here.
Keywords: susceptibility; multisite snp; method; snp genotyping ... See more keywords
POPDC2 a novel susceptibility gene for conduction disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2020.06.005
Abstract: Despite recent progress in the understanding of cardiac ion channel function and its role in inherited forms of ventricular arrhythmias, the molecular basis of cardiac conduction disorders often remains unresolved. We aimed to elucidate the… read more here.
Keywords: popdc2 novel; conduction disorders; novel susceptibility; conduction ... See more keywords
Tumor susceptibility gene 101 regulates predisposition to apoptosis via ESCRT machinery accessory proteins
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-12-0855
Abstract: The ESCRT-I protein TSG101 can mitigate endoplasmic reticulum stress–mediated apoptosis involving caspase 4/12 caused by MGRN1 depletion, probably contributing to neurodegeneration. TSG101 associates with ALIX to prevent predisposition to apoptosis, whereas ALIX–ALG-2 interaction favors a… read more here.
Keywords: 101 regulates; apoptosis; gene 101; tumor susceptibility ... See more keywords
Response by Veerman et al to Letter Regarding Article, "The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity".
Sign Up to like & getrecommendations! Published in 2017 at "Circulation Research"
DOI: 10.1161/circresaha.117.311674
Abstract: We welcome the opportunity to respond to the question raised by El-Battrawy et al in their letter concerning our study entitled “The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical… read more here.
Keywords: brugada syndrome; channel; gene hey2; letter ... See more keywords
Abstract 91: Moyamoya Disease Susceptibility Gene, RNF213 p.R4810K Variant, is a Common Risk Factor for Atherothrombotic Brain Infarction in a Japanese Population
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/str.49.suppl_1.91
Abstract: Background and Purpose: RNF213 has been identified as a susceptibility gene for moyamoya disease. The p.R4810K variant is found in about 80% of East Asian patients with moyamoya disease, and 20 - 2... read more here.
Keywords: moyamoya disease; r4810k variant; susceptibility gene;
The immunity of Meiwa kumquat against Xanthomonas citri is associated with a known susceptibility gene induced by a transcription activator-like effector
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008886
Abstract: Citrus canker caused by Xanthomonas citri subsp. citri (Xcc) is one of the most devastating diseases in citrus. Meiwa kumquat (Fortunella crassifolia) has shown a durable resistance against Xcc. Here, we aimed to characterize the… read more here.
Keywords: xcc; meiwa kumquat; citri; susceptibility gene ... See more keywords
The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12020450
Abstract: The multidomain protein encoded by the Tumor Susceptibility Gene 101 (TSG101) is ubiquitously expressed and is suggested to function in diverse intracellular processes. In this review, we provide a succinct overview of the main structural… read more here.
Keywords: 101 tsg101; susceptibility gene; tsg101; gene 101 ... See more keywords