Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency
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DOI: 10.1371/journal.pone.0243009
Abstract: Scrapie, a prion disease of sheep, is highly resistant to conventional deactivation. Numerous methods to deactivate scrapie have been tested in laboratory animal models, and adequate autoclave treatment can reduce or remove the infectivity of… read more here.
Keywords: susceptible vrq; autoclave treatment; scrapie; classical scrapie ... See more keywords