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Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-05892-0

Abstract: The heterogeneity of neurodegenerative diseases is a key confound to disease understanding and treatment development, as study cohorts typically include multiple phenotypes on distinct disease trajectories. Here we introduce a machine-learning technique—Subtype and Stage Inference… read more here.

Keywords: sustain; heterogeneity; neurodegenerative diseases; disease ... See more keywords