Sustained Clinical Remission of BRAF V600E-Mutated Langerhans Cell Histiocytosis With Multiorgan Involvement in an Infant Treated With Dabrafenib
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DOI: 10.1097/mph.0000000000003014
Abstract: Background: Above 50% of LCH cases show BRAF-mutations, which can be targeted by dabrafenib in refractory disease. Observations: Here, we report on a patient with neonatal multisystem, BRAF-mutated LCH refractory to conventional treatment with vinblastine… read more here.
Keywords: braf; dabrafenib; sustained clinical; clinical remission ... See more keywords
Sustained Clinical Efficacy and Mucosal Healing of Thiopurine Maintenance Treatment in Ulcerative Colitis: A Real-Life Study
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DOI: 10.1155/2018/4195968
Abstract: Background and Aims Thiopurines are commonly used for treating ulcerative colitis (UC), despite the fact that controlled evidence supporting their efficacy is limited. The aim of this study was to evaluate the long-term outcome of… read more here.
Keywords: maintenance; treatment; remission; mucosal healing ... See more keywords