Polyelectrolyte-Functionalized NanoMOFs for Highly Efficient Aqueous Lubrication and Sustained Drug Release.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202300089
Abstract: This paper demonstrated the hybridization of polyelectrolyte brushes with anti-inflammatory drug-loaded nanoMOFs that can achieve highly efficient aqueous lubrication and sustained drug release for the synergistic therapy of osteoarthritis (OA). Poly(3-sulfopropyl methacrylate potassium salt) (PSPMK)… read more here.
Keywords: pspmk; sustained drug; highly efficient; drug release ... See more keywords
Chitosan-cellulose hydrogel conjugated with L-histidine and zinc oxide nanoparticles for sustained drug delivery: Kinetics and in-vitro biological studies.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116101
Abstract: Functionalised nanohybrid hydrogel using L-Histidine (HIS) conjugated chitosan, phyto-synthesised zinc oxide nanoparticles (ZNPs) and dialdehyde cellulose (DAC) was formulated as a sustained drug delivery carrier for the polyphenol drugs - Naringenin (NRG), Quercetin (QE) and… read more here.
Keywords: hydrogel; drug delivery; zinc oxide; drug ... See more keywords
Improving sustained drug delivery from ophthalmic lens materials through the control of temperature and time of loading
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.02.017
Abstract: &NA; Although the possibility of using drug‐loaded ophthalmic lens to promote sustained drug release has been thoroughly pursued, there are still problems to be solved associated to the different alternatives. In this work, we went… read more here.
Keywords: ophthalmic lens; temperature; time; drug ... See more keywords
In-situ fast gelling formulation for oral sustained drug delivery of paracetamol to dysphagic patients.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.05.092
Abstract: Evaluation of the potential for oral sustained drug delivery of formulations with in-situ gelling properties is the main objective of the present investigation. Oral administration of aqueous dispersion of sodium alginate (1.5% w/v) containing calcium… read more here.
Keywords: oral sustained; drug delivery; drug; paracetamol ... See more keywords
Milling of Poorly Soluble Crystalline Drug Compounds to Generate Appropriate Particle Sizes for Inhaled Sustained Drug Delivery.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120116
Abstract: One of the simplest design concepts of inhaled sustained drug delivery to the lung is to utilize the slow dissolution of drug crystals with poor aqueous solubility. An optimum dissolution rate, and thereby a delivery… read more here.
Keywords: delivery; drug; size; particle ... See more keywords
Hairy Nanocellulose-Based Supramolecular Architectures for Sustained Drug Release.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01514
Abstract: The engineering of a new type of trifunctional biopolymer-based nanosponges polymerized by cross-linking beta-cyclodextrin ethylene diamine (βCD-EDA) with bifunctional hairy nanocellulose (BHNC) is reported herein. We refer to the highly cross-linked polymerized BHNC-βCD-EDA network as… read more here.
Keywords: sustained drug; cross; drug release; hairy nanocellulose ... See more keywords
One-step prepared nano-in-micro microcapsule delivery vehicle with sequential burst–sustained drug release for the targeted treatment of inflammatory bowel disease
Sign Up to like & getrecommendations! Published in 2021 at "Materials Chemistry Frontiers"
DOI: 10.1039/d1qm00589h
Abstract: A smart microcapsule for targeted therapy of IBD is prepared through droplet microfluidics. It can achieve sequential burst–sustained drug release, which is appropriate for the treatment of IBD from the point of view of pharmacology… read more here.
Keywords: microcapsule; sequential burst; drug release; burst sustained ... See more keywords
Recent advances in slow and sustained drug release for retina drug delivery
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2019.1618829
Abstract: ABSTRACT Introduction: Striking recent advance has occurred in the field of medical retina, greatly because intraocular drugs have been developed, enhancing their clinical efficacy while avoiding systemic side-effects. However, the burden of repeated intraocular administration… read more here.
Keywords: drug delivery; delivery; drug; delivery recent ... See more keywords
Polyurethane/halloysite nano tubes/sericin based electrospun nanocomposite for sustained drug release
Sign Up to like & getrecommendations! Published in 2023 at "Advances in Natural Sciences: Nanoscience and Nanotechnology"
DOI: 10.1088/2043-6262/acd3e6
Abstract: In this study, the feasibility of the production of electrospun nanofibre composite mainly for biomedical applications is reported. Biocompatible polyether-based polyurethane, natural proteinaceous polymer silk sericin (SS) and natural inorganic nanoclay halloysite as a drug… read more here.
Keywords: halloysite nano; sustained drug; drug release; release ... See more keywords
FORMULATION, OPTIMIZATION AND IN VITRO EVALUATION OF 5-FLUOROURACIL LOADED LIQUORICE CRUDE PROTEIN NANOPARTICLES FOR SUSTAINED DRUG DELIVERY USING BOX-BEHNKEN DESIGN
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2021v13i1.39932
Abstract: Objective: To formulate, optimize and evaluate 5-fluorouracil loaded liquorice crude protein nanoparticles for sustained drug delivery using Box-Behnken design. Methods: 5-fluorouracil (5-FU) loaded liquorice crude protein (LCP) nanoparticles were prepared by desolvation method using ethanol-water… read more here.
Keywords: fluorouracil; fluorouracil loaded; drug; crude protein ... See more keywords
Intravitreal Injectable Hydrogels for Sustained Drug Delivery in Glaucoma Treatment and Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14122359
Abstract: Glaucoma is extensively treated with topical eye drops containing drugs. However, the retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly influenced before reaching the targeted area sufficiently,… read more here.
Keywords: glaucoma treatment; sustained drug; drug delivery; drug ... See more keywords