Impact of sustained de novo lipogenesis on mitochondrial dysfunction and hepatocellular redox during fatty liver disease
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DOI: 10.1152/physiol.2023.38.s1.5730204
Abstract: Dysfunctional mitochondrial metabolism and sustained de novo lipogenesis are characteristic of non-alcoholic fatty liver disease (NAFLD), a common comorbidity of obesity and type 2 diabetes. We hypothesize that sustained de novo lipogenesis, through its biochemical… read more here.
Keywords: physiology; novo lipogenesis; lipogenesis; tca cycle ... See more keywords