Injectable Supramolecular Ureidopyrimidinone Hydrogels Provide Sustained Release of Extracellular Vesicle Therapeutics.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900847
Abstract: Extracellular vesicles (EVs) are small vesicles secreted by cells and have gained increasing interest as both drug delivery vehicles or as cell-free therapeutics for regenerative medicine. To achieve optimal therapeutic effects, strategies are being developed… read more here.
Keywords: provide sustained; hydrogel; hydrogels provide; sustained release ... See more keywords
Engineering Lipid Spherulites for the Sustained Release of Highly Dosed Small Hydrophilic Compounds
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202249
Abstract: Currently, there is a lack of parenteral sustained release formulations for the delivery of highly dosed small hydrophilic drugs. Therefore, parenteral lipid spherulites are engineered capable of entrapping large amounts of such compounds and spontaneously… read more here.
Keywords: dosed small; small hydrophilic; lipid spherulites; highly dosed ... See more keywords
Sustained‐Release Hydrogen‐Powered Bilateral Microneedles Integrating CD‐MOFs for In Situ Treating Allergic Rhinitis
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400637
Abstract: Glucocorticoids are widely used for treating allergic rhinitis, but conventional intranasal administration encounters unfavorable nasal cilia clearance and nasal mucosal barrier. Herein, a bilateral microneedle patch is fabricated for delivering cyclodextrin‐based metal–organic frameworks (CD‐MOF) encapsulating… read more here.
Keywords: allergic rhinitis; sustained release; rhinitis; release hydrogen ... See more keywords
Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202503698
Abstract: Effective management of postoperative pain and wound healing presents significant challenges in clinical settings, driving the need for innovative therapeutic approaches. The analgesic and wound healing effects of hydrogen (H2) have gradually been recognized; however,… read more here.
Keywords: sustained release; release; pain; wound healing ... See more keywords
Mask‐Based Separator with Sustained‐Release LiNO 3 as Dendrite Growth Barrier for Potassium Metal Battery
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Energy Materials"
DOI: 10.1002/aenm.202300734
Abstract: Separators with low‐cost, superior mechanical properties, such as nanofiber materials, are considered a viable option for solving the dendritic problem in alkali metal batteries. Consuming the dendrites rather than blocking them underpins the long‐life stable… read more here.
Keywords: potassium metal; dendrite growth; mask; separator ... See more keywords
Encapsulation of salicylic acid in acylated low molecular weight chitosan for sustained release topical application
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45273
Abstract: Acylated low molecular weight chitosan was used to encapsulate salicylic acid (SA) for sustained release in topical delivery. Chitosan nanoparticles were prepared from the depolymerization of commercial chitosan and further acylated with short alkyl chains.… read more here.
Keywords: low molecular; weight chitosan; chitosan; sustained release ... See more keywords
Nanoemulsions for increased penetrability and sustained release of leishmanicidal compounds.
Sign Up to like & getrecommendations! Published in 2023 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300108
Abstract: In the last decade, the World Health Organization has driven the development of drugs for topical use in patients with cutaneous leishmaniasis (CL), the most prevalent clinical form of leishmaniasis, a neglected tropical disease. The… read more here.
Keywords: penetrability sustained; nanoemulsions increased; tc1 tc2; release ... See more keywords
Pharmacokinetic and Bioequivalent Study of Potassium Chloride Sustained‐Release Tablet Under Different Dietary Conditions in Healthy Chinese Subjects
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1180
Abstract: Potassium (K+) is an endogenous substance that is an essential dietary component. However, the interaction between dietary arrangements and specific effects of dietary K+ intake in bioequivalence studies remains unclear. To investigate the influence of… read more here.
Keywords: dietary conditions; potassium chloride; sustained release; healthy chinese ... See more keywords
Pharmacokinetics and Bioequivalence Evaluation of Trazodone Hydrochloride Sustained‐Release Tablets in Healthy Chinese Volunteers
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1490
Abstract: The aim of this study was to investigate the pharmacokinetics, bioequivalence, and safety of generic trazodone hydrochloride sustained‐release tablet and its reference listed product in healthy Chinese subjects. An open, randomized, single‐dose, and 2‐period crossover… read more here.
Keywords: bioequivalence; trazodone hydrochloride; sustained release; hydrochloride sustained ... See more keywords
Comparison of the Pharmacokinetics of a Fixed‐Dose Combination of Rosuvastatin/Metformin Sustained‐Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.841
Abstract: Fixed‐dose combination (FDC) drugs with various dose combinations for the treatment of type 2 diabetes mellitus and dyslipidemia are currently in demand. We compared the pharmacokinetic (PK) profiles of the rosuvastatin/metformin sustained‐release (10/1000 mg) FDC… read more here.
Keywords: rosuvastatin metformin; metformin; sustained release; metformin sustained ... See more keywords
Physicochemical properties, antioxidant activities and in vitro sustained release behavior of co-encapsulated liposomes as vehicle for vitamin E and β-carotene.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11925
Abstract: BACKGROUND In this study the potential of liposomes as vitamin E (VE) and β-carotene (βC) delivery system was examined. The co-encapsulated liposomes of βC and VE (L-VE-βC) were prepared and characterized. Their antioxidant properties were… read more here.
Keywords: release behavior; vitamin carotene; sustained release; release ... See more keywords