Sustained Upregulation of Endothelial Nox4 Mediates Retinal Vascular Pathology in Type 1 Diabetes.
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DOI: 10.2337/db22-0194
Abstract: NADPH oxidase 4 (Nox4) is a major source of reactive oxygen species (ROS) in retinal endothelial cells (ECs) and is upregulated under hyperglycemic and hypoxic conditions. However, the role of endothelial Nox4 upregulation in long-term… read more here.
Keywords: vascular pathology; retinal vascular; pathology; endothelial nox4 ... See more keywords