SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation
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DOI: 10.1002/2211-5463.13373
Abstract: The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim). Since cellular replication protein… read more here.
Keywords: fragment synthesis; okazaki fragment; synthesis; rpa ... See more keywords
Antibodies Against Mimotopes of Simian Virus 40 Large T Antigen, the Oncoprotein, in Serum Samples From Elderly Healthy Subjects
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DOI: 10.1002/jcp.25405
Abstract: Simian Virus 40 (SV40), a monkey polyomavirus, was administered to human populations by early anti‐poliomylitis vaccines contaminated by this small DNA tumor virus. Data on SV40 infection in humans remain controversial. Elderly subjects represent an… read more here.
Keywords: infection; oncoprotein; antigen; virus ... See more keywords
Simian virus 40 DNA in immunocompetent children with respiratory disease
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DOI: 10.1002/jmv.27973
Abstract: Evidence of Simian virus 40 (SV40) DNA sequences or gene products has been reported in a variety of organ systems in humans. However, the route of transmission and the significance of SV40 polyomavirus infection in… read more here.
Keywords: dna; infection; sv40; respiratory tract ... See more keywords
Does the Evidence Support the Existence of the Simian Polyomavirus SV40 Vp4 Viroporin?
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DOI: 10.1128/msphere.00019-20
Abstract: The simian polyomavirus SV40 was reported to express Vp4, an N-terminally truncated form of the minor capsid proteins Vp2 and Vp3. Since a missense mutation of the putative Vp4 start codon (Vp2M228I) was found to… read more here.
Keywords: sv40; polyomavirus sv40; simian polyomavirus; release ... See more keywords
SV40 Transfected Human Anterior Cruciate Ligament Derived Ligamentocytes—Suitable as a Human in Vitro Model for Ligament Reconstruction?
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DOI: 10.3390/ijms21020593
Abstract: Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular but tissue engineering (TE) requires high cell numbers. Simian virus (SV) 40 tumor (T) antigen expression could… read more here.
Keywords: anterior cruciate; non transfected; model; expression ... See more keywords