SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding
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DOI: 10.1073/pnas.2216240119
Abstract: Significance The initiation of replication of duplex DNA genomes requires that the duplex be opened up for helicase unwinding and to enable assembly of replisome machines that act at DNA replication forks. Cellular and many… read more here.
Keywords: duplex dna; shearing mechanism; dna; dna shearing ... See more keywords