Transcriptional Alterations in X-Linked Dystonia–Parkinsonism Caused by the SVA Retrotransposon
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DOI: 10.3390/ijms23042231
Abstract: X-linked dystonia–parkinsonism (XDP) is a severe neurodegenerative disorder that manifests as adult-onset dystonia combined with parkinsonism. A SINE-VNTR-Alu (SVA) retrotransposon inserted in an intron of the TAF1 gene reduces its expression and alters splicing in… read more here.
Keywords: dystonia parkinsonism; transcriptional alterations; linked dystonia; parkinsonism ... See more keywords