SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105042
Abstract: The Na+-dependent Vitamin C transporter 2 (SVCT2) is expressed in the plasma and mitochondrial membranes of various cell types. This notion was also established in proliferating C2C12 myoblasts (Mb), in which the transporter was characterised… read more here.
Keywords: membrane transport; svct2; ascorbic acid; expression ... See more keywords
ATRX-dependent SVCT2 mediates macrophage infiltration in the glioblastoma xenograft model.
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DOI: 10.1152/jn.00486.2021
Abstract: Alpha thalassemia/mental retardation syndrome X-linked (ATRX) mutation impairs DNA damage repair in glioblastoma (GBM), making these cells more susceptible to treatment, which may contribute to the survival advantage in GBM patients containing ATRX mutations. To… read more here.
Keywords: dependent svct2; model; svct2; atrx dependent ... See more keywords
Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer
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DOI: 10.7150/jca.57463
Abstract: The sodium-dependent vitamin C transporter 2 (SVCT2) surface glycoprotein regulates ascorbate accumulation in the plasma, often resulting in the induction of cancer cell death. Therefore, high expression of this gene associates with increased overall survival… read more here.
Keywords: colorectal cancer; svct2; proliferation; svct2 e264k ... See more keywords