Long noncoding RNA PVT1 accelerates the growth of placental trophoblasts in preeclampsia through the microRNA‐24‐3p/HSD11B2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23575
Abstract: Long noncoding RNA plasmacytoma variant translocation 1 (PVT1) is essential for the maintenance of normal functions of trophoblasts in preeclampsia (PE). This study aims to decipher the concrete mechanism of PVT1 with the microRNA‐24‐3p/Type‐2 11β‐hydroxysteroid… read more here.
Keywords: hsd11b2; htr svneo; growth; pvt1 ... See more keywords
Effect and mechanism of microRNA‐515‐5p in proliferation and apoptosis of trophoblast cells in preeclampsia via manipulating histone deacetylase 2
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23649
Abstract: Preeclampsia (PE) refers to a pregnancy‐specific disease that begins with the placenta. Differentially expressed microRNAs (miRs) are a feature of PE. This study tried to elicit the functional mechanism of miR‐515‐5p in trophoblast cell behaviors… read more here.
Keywords: htr svneo; proliferation apoptosis; svneo cells; mir 515 ... See more keywords
Cadmium cytotoxicity and possible mechanisms in human trophoblast HTR‐8/SVneo cells
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DOI: 10.1002/tox.23110
Abstract: The accumulation of cadmium (Cd) in the human body through food chain can lead to adverse pregnancy outcomes. In this study, Cd cytotoxicity and its mechanisms in HTR‐8/SVneo cells were investigated. Cd disrupted the cellular… read more here.
Keywords: htr svneo; cytotoxicity possible; possible mechanisms; svneo cells ... See more keywords
Methylmercury cytotoxicity and possible mechanisms in human trophoblastic HTR-8/SVneo cells.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111520
Abstract: Methylmercury (MeHg) exposure during pregnancy can lead to adverse outcomes, including miscarriage and intrauterine growth retardation. In this study, MeHg cytotoxicity and its mechanisms in HTR-8/SVneo cells were investigated. MeHg inhibited HTR-8/SVneo cell viability and… read more here.
Keywords: svneo cells; cytotoxicity; htr svneo; mehg ... See more keywords
Astragaloside IV protects human trophoblast HTR8/SVneo cells from H2O2-Induced oxidative stress via Nrf2-Keap1-p62 feedback loop
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104621
Abstract: Abstract Preeclampsia is one of the serious complications of pregnancy and is the main cause of maternal death. Accumulation of trophoblastic reactive oxygen species (ROS) and placental dysfunction are the potential pathogenic bases of early-onset… read more here.
Keywords: svneo cells; oxidative stress; htr8 svneo; h2o2 induced ... See more keywords
MiR-222-5p promotes the growth and migration of trophoblasts by targeting AHNAK.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202011_23578
Abstract: OBJECTIVE The purpose of this study was to detect microRNA-222-5p (miR-222-5p) levels in placental tissues of preeclampsia (PE) pregnancies, and to explore the role of miR-222-5p in the proliferative and migratory potentials of trophoblast cell… read more here.
Keywords: mir 222; htr svneo; proliferative migratory; svneo cells ... See more keywords
Psoralen Promotes Proliferation, Migration, and Invasion of Human Extravillous Trophoblast Derived HTR-8/Svneo Cells in vitro by NF-κB Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.804400
Abstract: Recurrent spontaneous abortion (RSA) is a kind of pathological pregnancy, and abnormal function of trophoblast cells may be related to a variety of pregnancy complications including RSA. Psoralen is an effective ingredient extracted from Cullen… read more here.
Keywords: htr svneo; migration invasion; svneo cells;
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9020121
Abstract: Pregnancy complications are associated with oxidative stress induced by accumulation of trophoblastic ROS in the placenta. We employed the human trophoblast HTR8/SVneo cell line to determine the effect of curcumin pre-treatment on H2O2-induced oxidative damage… read more here.
Keywords: svneo cells; htr8 svneo; curcumin; oxidative stress ... See more keywords
[Expression of lncRNA MIR210HG in preeclampsia placental tissue and its functional analysis].
Sign Up to like & getrecommendations! Published in 2021 at "Zhonghua fu chan ke za zhi"
DOI: 10.3760/cma.j.cn112141-20210118-00029
Abstract: Objective: To investigate the differential expression of long non-coding RNA (lncRNA) in placental tissues of women with preeclampsia (PE) and the effect of MIR210HG on the biological function of HTR8/SVneo cells. Methods: A total of… read more here.
Keywords: analysis; group; svneo cells; expression ... See more keywords