Identification of NeuN immunopositive cells in the adult mouse subventricular zone
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24463
Abstract: In the adult rodent subventricular zone (SVZ), there are neural stem cells (NSCs) and the specialized neurogenic niche is critical to maintain their stemness. To date, many cellular and noncellular factors that compose the neurogenic… read more here.
Keywords: subventricular zone; adult mouse; svz; immunopositive cells ... See more keywords
TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23253
Abstract: Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor β1 (TGF‐β) signaling pathways play critical roles in controlling these cell fate decisions. TGF‐β… read more here.
Keywords: cell; interaction notch; svz; progenitor ... See more keywords
In vitro characterization of subventricular zone isolated neural stem cells, from adult monkey and rat brain
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology Reports"
DOI: 10.1007/s11033-021-06201-7
Abstract: Neural stem cells (NSCs) are multipotent, self-renewable cells who are capable of differentiating into neurons, astrocytes, and oligodendrocytes. NSCs reside at the subventricular zone (SVZ) of the adult brain permanently to guarantee a lifelong neurogenesis… read more here.
Keywords: subventricular zone; svz nscs; svz; stem cells ... See more keywords
GPER1 Signaling Initiates Migration of Female V-SVZ-Derived Cells
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101077
Abstract: Summary In the rodent ventricular-subventricular zone (V-SVZ) neurons are generated throughout life. They migrate along the rostral migratory stream (RMS) into the olfactory bulb before their final differentiation into interneurons and integration into local circuits.… read more here.
Keywords: svz derived; gper1 signaling; svz; signaling initiates ... See more keywords
Prognostic analysis of patients who underwent gross total resection of newly diagnosed glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2018.01.009
Abstract: Despite cumulative evidence supporting the idea that gross total resection (GTR) contributes to prolonged survival of patients with glioblastoma (GBM), the survival outcome of such patients remains unsatisfactory. To develop more effective postoperative therapeutic strategies… read more here.
Keywords: newly diagnosed; total resection; gross total; svz ... See more keywords
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1811825116
Abstract: Significance Recovery after stroke involves remodeling in brain tissue adjacent to the stroke site. In this remodeling, neurogenesis after stroke involves the formation of new neurons. The role of neurogenesis in stroke recovery and the… read more here.
Keywords: recovery; neurogenesis; svz; recovery stroke ... See more keywords
Single-cell analysis of the postnatal dorsal V-SVZ reveals a role for Bmpr1a signaling in silencing pallial germinal activity
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.abq7553
Abstract: The ventricular-subventricular zone (V-SVZ) is the largest neurogenic region of the postnatal forebrain, containing neural stem cells (NSCs) that emerge from both the embryonic pallium and subpallium. Despite of this dual origin, glutamatergic neurogenesis declines… read more here.
Keywords: role; postnatal dorsal; single cell; activity ... See more keywords
Identifying Differential Expression Genes and Prognostic Signature Based on Subventricular Zone Involved Glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.912227
Abstract: Background: Studies have suggested that glioblastoma (GBM) cells originate from the subventricular zone (SVZ) and that GBM contact with the SVZ correlated with worse prognosis and higher recurrence. However, research on differentially expressed genes (DEGs)… read more here.
Keywords: signature; expression; subventricular zone; risk ... See more keywords
In-vivo characterization of macro- and microstructural injury of the subventricular zone in relapsing-remitting and progressive multiple sclerosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1112199
Abstract: Introduction The subventricular zone (SVZ) represents one of the main adult brain neurogenesis niche. In-vivo imaging of SVZ is very challenging and little is known about MRI correlates of SVZ macro- and micro-structural injury in… read more here.
Keywords: relapsing remitting; subventricular zone; injury; caudate ... See more keywords
The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.790976
Abstract: Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with standard care; however, cases of successful treatment offer hope that an enhanced understanding of the pathology will improve the prognosis.… read more here.
Keywords: maintenance modeling; glioblastoma; genesis maintenance; subventricular zone ... See more keywords
Therapy Resistance of Glioblastoma in Relation to the Subventricular Zone: What Is the Role of Radiotherapy?
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061677
Abstract: Simple Summary Glioblastoma is a highly aggressive form of brain tumors characterized by rapid growth. The subventricular zone (SVZ) is an important region in the brain for processes such as neurogenesis, learning and memory, and… read more here.
Keywords: glioblastoma; brain; subventricular zone; versus months ... See more keywords