PGC-1α Regulates Cell Proliferation and Invasion via AKT/GSK-3β/β-catenin Pathway in Human Colorectal Cancer SW620 and SW480 Cells
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DOI: 10.21873/anticanres.13995
Abstract: Background/Aim: Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a master regulator of mitochondrial biogenesis and metabolism. We investigated the effect of PGC-1α knockdown in the human colorectal cancer cell line SW620, which highly expresses… read more here.
Keywords: invasion; cell proliferation; akt gsk; cell ... See more keywords
Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells
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DOI: 10.3390/ph15101299
Abstract: A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated in human colon adenocarcinoma cells (SW480 and SW620) and non-malignant cell lines… read more here.
Keywords: colorectal cancer; chemopreventive potential; sw620; genistein hybrids ... See more keywords