A survey of swainsonine content in Swainsona species
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DOI: 10.1071/rj16088
Abstract: The indolizidine alkaloid swainsonine is an inhibitor of α-mannosidase and mannosidase II that causes lysosomal storage disease and alters glycoprotein processing. Several plant species worldwide contain swainsonine, grazing these plants may cause severe toxicosis in… read more here.
Keywords: chromatography; swainsona species; mass spectrometry; swainsonine ... See more keywords
Phylogenetic Comparison of Swainsonine Biosynthetic Gene Clusters among Fungi
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DOI: 10.3390/jof8040359
Abstract: Swainsonine is a cytotoxic alkaloid produced by fungi. Genome sequence analyses revealed that these fungi share an orthologous gene cluster, SWN, necessary for swainsonine biosynthesis. To investigate the SWN cluster, the gene sequences and intergenic… read more here.
Keywords: swainsonine; cluster; fungi phylogenetic; gene ... See more keywords
Host-Species Variation and Environment Influence Endophyte Symbiosis and Mycotoxin Levels in Chinese Oxytropis Species
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DOI: 10.3390/toxins14030181
Abstract: Oxytropis plants are widely distributed in the grasslands in northern China. Some Oxytropis species have been reported to contain the mycotoxin swainsonine, an alkaloid which causes poisoning in livestock, referred to as locoism. Previous studies… read more here.
Keywords: oxytropis species; symbiosis; influence endophyte; swainsonine ... See more keywords