Development of algorithm for diagnosis of cystic fibrosis in absence of sweat chloride testing in resource‐limited setting
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DOI: 10.1002/ppul.26137
Abstract: To develop a diagnostic algorithm for cystic fibrosis (CF) in the setting of unavailability of sweat chloride, based on clinical features and basic laboratory investigations. read more here.
Keywords: development algorithm; algorithm diagnosis; cystic fibrosis; sweat chloride ... See more keywords
Gradual increase in sweat chloride concentration is associated with a higher risk of CRMS/CFSPID to CF reclassification
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DOI: 10.1002/ppul.26296
Abstract: Universal implementation of cystic fibrosis (CF) newborn screening (NBS) has led to the diagnostic dilemma of infants with CF screen‐positive, inconclusive diagnosis (CFSPID), with limited guidance regarding prognosis and standardized care. Rates of reclassification from… read more here.
Keywords: reclassification; sweat chloride; gradual increase; increase sweat ... See more keywords
Sweat chloride quantification using capillary electrophoresis
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DOI: 10.1016/j.plabm.2018.e00114
Abstract: Background Cystic fibrosis (CF) is the less rare and severe genetic disease among the European population. Biochemical diagnosis of CF is based on the demonstration of increased chloride concentration in sweat samples, obtained during the… read more here.
Keywords: capillary electrophoresis; sweat; method; sweat chloride ... See more keywords
A step forward for an intermediate cystic fibrosis population
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DOI: 10.1183/13993003.01040-2022
Abstract: Cystic fibrosis (CF) is a life-long and life-shortening disease, best treated with early interventions to prevent complications across multiple organs and to extend the lifespan of this population. In the USA and Europe, the diagnosis… read more here.
Keywords: sweat chloride; step forward; population; fibrosis ... See more keywords