Articles with "swine model" as a keyword



Safety Assessment of a 1940 nm Tm:YAP Laser for Fractional Skin Ablation in a Swine Model

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Published in 2025 at "Lasers in Surgery and Medicine"

DOI: 10.1002/lsm.70022

Abstract: This exploratory study was aimed to evaluate the safety and preliminary efficacy of Epicare, a 1940 nm thulium‐doped yttrium aluminum perovskite (Tm:YAP) laser, for fractional skin ablation in a swine model. The goal was to assess… read more here.

Keywords: yap laser; swine model; skin ablation; laser fractional ... See more keywords
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A Swine Model of Filter-Assisted Caval Thrombosis for Endovascular Thrombectomy Using AngioJet

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Published in 2020 at "Journal of Cardiovascular Translational Research"

DOI: 10.1007/s12265-020-10059-8

Abstract: To assess the feasibility of creating swine model of filter-assisted caval thrombosis and to evaluate the efficacy in removing clot in this model using rheolytic thrombectomy. The model was created by implanting a filter into… read more here.

Keywords: swine model; model; filter; caval thrombosis ... See more keywords

Development and pre-clinical evaluation in the swine model of a mucosal vaccine tablet for human influenza viruses: A proof-of-concept study.

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Published in 2018 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.01.021

Abstract: Liquid vaccine formulations present some disadvantages such as stability problems, cold chain requirement or administration by trained personnel. Vaccine formulated as tablets would present a wide range of progress such as an increase stability that… read more here.

Keywords: human influenza; influenza viruses; swine model; influenza ... See more keywords

Noninvasive Stereotactic Radiotherapy for Renal Denervation in a Swine Model.

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Published in 2019 at "Journal of the American College of Cardiology"

DOI: 10.1016/j.jacc.2019.07.053

Abstract: BACKGROUND Catheter-based renal denervation (RDN) has achieved promising outcomes to treat hypertension in recent randomized controlled trials. OBJECTIVES The purpose of this study was to assess the feasibility, efficacy, and safety of noninvasive stereotactic body… read more here.

Keywords: swine model; renal denervation; radiotherapy; noninvasive stereotactic ... See more keywords

Multiomics Signatures of Coagulopathy in a Polytrauma Swine Model Contrasted with Severe Multisystem Injured Patients.

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Published in 2024 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.3c00581

Abstract: Trauma-induced coagulopathy (TIC) is a leading contributor to preventable mortality in severely injured patients. Understanding the molecular drivers of TIC is an essential step in identifying novel therapeutics to reduce morbidity and mortality. This study… read more here.

Keywords: swine model; model; injured patients; polytrauma swine ... See more keywords

Radiation-induced Hounsfield unit change correlates with dynamic CT perfusion better than 4DCT-based ventilation measures in a novel-swine model

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-92609-x

Abstract: To analyze radiation induced changes in Hounsfield units and determine their correlation with changes in perfusion and ventilation. Additionally, to compare the post-RT changes in human subjects to those measured in a swine model used… read more here.

Keywords: perfusion; swine model; radiation induced; model ... See more keywords
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Development and characterization of a new swine model of invasive pneumococcal pneumonia

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Published in 2021 at "Lab Animal"

DOI: 10.1038/s41684-021-00876-y

Abstract: Streptococcus pneumoniae is the most common microbial cause of community-acquired pneumonia. Currently, there are no available models of severe pneumococcal pneumonia in mechanically ventilated animals to mimic clinical conditions of critically ill patients. We studied… read more here.

Keywords: pneumococcal pneumonia; swine model; new swine; infected pigs ... See more keywords

Therapeutic Effects of Amnion-Conjugated Chitosan-Alginate Membranes on Diabetic Wounds in an Induced Diabetic Swine Model: An In Vitro and In Vivo Study

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Published in 2022 at "Archives of Plastic Surgery"

DOI: 10.1055/s-0042-1744429

Abstract: Background  Chitosan (CS) is a well-known antimicrobial dressing material. Moreover, widely used amniotic membranes contain growth factors beneficial for wound healing. Herein, we created a novel amnion-conjugated CS-alginate membrane dressing and tested its wound healing… read more here.

Keywords: wound healing; swine model; amnion; amnion conjugated ... See more keywords

Intramuscular dimethyl trisulfide: efficacy in a large swine model of acute severe cyanide toxicity

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Published in 2019 at "Clinical Toxicology"

DOI: 10.1080/15563650.2018.1511800

Abstract: Abstract Background: Cyanide is a deadly compound used as a terrorist agent. Current FDA approved antidotes require intravenous administration, limiting their utility in a mass casualty scenario. Dimethyl trisulfide (DMTS), a sulfur-based molecule, binds cyanide… read more here.

Keywords: dmts; cyanide toxicity; swine model; model acute ... See more keywords

Safety and effectiveness of endobiliary radiofrequency ablation according to the different power and target temperature in a swine model

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Published in 2017 at "Journal of Gastroenterology and Hepatology"

DOI: 10.1111/jgh.13472

Abstract: Endobiliary radiofrequency ablation (EB‐RFA) is a new endoscopic palliation and adjunctive tool. Although EB‐RFA is performed worldwide, a possibility of iatrogenic thermal injury leading to perforation or bleeding still remains. Therefore, we aimed to assess… read more here.

Keywords: temperature; swine model; endobiliary radiofrequency; radiofrequency ablation ... See more keywords

Abstract Tu008: Efficient Intramyocardial Delivery of EV-Encapsulated AAVs to Target Cardiomyocytes in a Pre-Clinical Swine Model

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Published in 2024 at "Circulation Research"

DOI: 10.1161/res.135.suppl_1.tu008

Abstract: Background: Adeno-associated viruses (AAV) have been widely used to deliver therapeutic genes to the heart due to their safety and efficacy. However, a major obstacle to their successful gene delivery is the presence of neutralizing… read more here.

Keywords: swine model; clinical swine; delivery; pre clinical ... See more keywords