KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer
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DOI: 10.1158/0008-5472.can-22-1444
Abstract: A gain-of-function epigenetic switch that disrupts differentiation is triggered by inactivating KDM6A mutations in bladder cancer and can serve as a potential target for novel therapies. read more here.
Keywords: epigenetic switch; switch disrupts; differentiation; bladder cancer ... See more keywords