Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation
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DOI: 10.1093/nar/gky242
Abstract: Abstract Precursor message RNA (pre-mRNA) splicing is executed by the spliceosome, a large ribonucleoprotein (RNP) machinery that is comparable to the ribosome. Driven by the rapid progress of cryo-electron microscopy (cryo-EM) technology, high resolution structures… read more here.
Keywords: spliceosome assembly; terminal domain; switch loop; structural dynamics ... See more keywords