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Published in 2022 at "Brain"
DOI: 10.1093/brain/awac049
Abstract: Abstract RAC1 is a highly conserved Rho GTPase critical for many cellular and developmental processes. De novo missense RAC1 variants cause a highly variable neurodevelopmental disorder. Some of these variants have previously been shown to…
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Keywords:
rac1 variants;
switch region;
rac1;
developmental syndrome ... See more keywords
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1
Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01732-17
Abstract: ABSTRACT Scrub typhus is a potentially lethal infection caused by the obligate intracellular bacterium Orientia tsutsugamushi. Reports on the emergence of doxycycline-resistant strains highlight the urgent need to develop novel antiinfectives against scrub typhus. Corallopyronin…
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Keywords:
orientia tsutsugamushi;
vivo;
tsutsugamushi;
rna polymerase ... See more keywords
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0
Published in 2020 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00125-20
Abstract: Activation-induced cytidine deaminase (AID) initiates immunoglobulin (Ig) class switch recombination (CSR), somatic hypermutation (SHM), and gene conversion by converting DNA cytosines to uracils at specific genomic regions. In this study, we examined AID footprints across…
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Keywords:
switch region;
class switch;
aid;
deamination ... See more keywords