Peroxiredoxin 4 as a switch regulating PTEN/AKT axis in alveolar macrophages activation
Sign Up to like & getrecommendations! Published in 2025 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-025-02454-x
Abstract: Phosphatase and tensin homolog (PTEN) is a critical inhibitor of the PI3K/AKT signaling pathway, yet its direct upstream regulators remain poorly defined. In this study, we investigated the role of peroxiredoxin 4 (PRDX4) in alveolar… read more here.
Keywords: fibrosis; switch regulating; peroxiredoxin; alveolar macrophages ... See more keywords
Where and how many: evolutionary diversification of a molecular switch regulating flagellar patterns.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of bacteriology"
DOI: 10.1128/jb.00329-25
Abstract: ABSTRACT Flagella are rotating organelles of locomotion that enable bacteria to navigate their environments. They are positioned at various locations and in differing numbers across the bacterial surface, a characteristic known as the “flagellation pattern.”… read more here.
Keywords: evolutionary diversification; molecular switch; switch regulating; many evolutionary ... See more keywords