Switchable assembly and function of antibody complexes in vivo using a small molecule
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2117402119
Abstract: Significance Reported here, we describe a molecular protein technology to enable switchable assembly of functional antibody complexes. This approach, which we call ligand-induced transient engagement (LITE), allows for control of an antibody’s intended function in… read more here.
Keywords: small molecule; function; antibody complexes; switchable assembly ... See more keywords