A Traceless Heterocyclic Amine Mediator in Regioselectivity-Switchable Formal [1 + 2 + 2] Cycloaddition Reaction to 1,3,4- and 1,4,5-Trisubstituted Pyrazoles.
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DOI: 10.1021/acs.orglett.2c04227
Abstract: Switchable multicomponent reactions have been attractive tools for the construction of compound libraries with skeleton diversity and complexity by slightly changing the reaction conditions. Described herein is a regioselectivity-switchable formal [1 + 2 + 2]… read more here.
Keywords: reaction; regioselectivity; switchable formal; regioselectivity switchable ... See more keywords