Iodine-Mediated Electrochemical C(sp2)-H Amination: Switchable Synthesis of Indolines and Indoles.
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DOI: 10.1021/acs.orglett.0c01821
Abstract: A metal-free electrochemical intramolecular C(sp2)-H amination using iodine as a mediator was developed. This method enables a switchable synthesis of indoline and indole derivatives, respectively, from easily available 2-vinyl anilines. read more here.
Keywords: switchable synthesis; iodine mediated; sp2 amination;
Ag-Catalyzed Switchable Synthesis of Site-Specifically Functionalized Pyrroles via Azafulvenium Intermediates.
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DOI: 10.1021/acs.orglett.4c01437
Abstract: Here, we present a versatile, silver-catalyzed multi-auto-tandem reaction involving enamines, alkynals, and nucleophiles, utilizing the highly reactive intermediate azafulvenium. This method allows for flexible and switchable regiodivergent reactions through either intermolecular or intramolecular nucleophilic attacks,… read more here.
Keywords: site specifically; synthesis site; site; azafulvenium ... See more keywords
Manganese-Catalyzed and Base-Switchable Synthesis of Amines or Imines via Borrowing Hydrogen or Dehydrogenative Condensation
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DOI: 10.1021/acscatal.8b02530
Abstract: The use of earth-abundant transition metals as a noble metal replacement in catalysis is especially interesting if different catalytic reactivity is observed. We report, here, on the selective manganese-catalyzed base-switchable synthesis of N-alkylated amines or… read more here.
Keywords: hydrogen; manganese catalyzed; base switchable; base ... See more keywords
Regio- and Stereoselective Switchable Synthesis of (E)- and (Z)-N-Carbonylvinylated Pyrazoles
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DOI: 10.3390/molecules28114347
Abstract: Regio- and stereoselective switchable synthesis of (E)- and (Z)-N-carbonylvinylated pyrazoles is first developed by using the Michael addition reaction of pyrazoles and conjugated carbonyl alkynes. Ag2CO3 plays a key role in the switchable synthesis of… read more here.
Keywords: synthesis carbonylvinylated; carbonylvinylated pyrazoles; regio stereoselective; stereoselective switchable ... See more keywords