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   Articles with "switching therapy" as a keyword



Safety of Rituximab biosimilar (Riximyo®) following a single switch from the reference product in patients with Non-Hodgkin’s lymphoma: a retrospective study

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recommendations! Published in 2024 at "Annals of Hematology"

DOI: 10.1007/s00277-024-05981-9

Abstract: Unlike small molecule drugs and generic products, the active component of biologics and biosimilars are not identical chemical entities. Despite bioequivalence, there is limited evidence in clinical practice (i.e. Phase IV post-marketing surveillance) regarding the… read more here.

Keywords: product; therapy; reference; switching therapy ... See more keywords

Switching therapy from bevacizumab to aflibercept for the management of persistent diabetic macular edema

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recommendations! Published in 2017 at "Graefe's Archive for Clinical and Experimental Ophthalmology"

DOI: 10.1007/s00417-017-3624-y

Abstract: PurposeTo evaluate the visual and anatomical outcomes following switching therapy from bevacizumab to aflibercept in patients with persistent diabetic macular edema (DME).MethodsPatients with DME and central macular thickness (CMT) >300 μm on spectral domain optical coherence… read more here.

Keywords: bevacizumab aflibercept; bevacizumab; diabetic macular; switching therapy ... See more keywords

Cefpodoxime proxetil as a therapeutic option in switching therapy for infective endocarditis in children: case reports and literature review

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recommendations! Published in 2019 at "Journal of Chemotherapy"

DOI: 10.1080/1120009x.2019.1603797

Abstract: Infective endocarditis (IE) is uncommon in children, affecting predominantly subjects with congenital heart disease (CHD) and patients with indwelling central lines. The principles of antibiotic treatment in paediatric population are similar to those in adults.… read more here.

Keywords: switching therapy; therapy; infective endocarditis; cefpodoxime proxetil ... See more keywords
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Splice-Switching Therapy for Spinal Muscular Atrophy

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recommendations! Published in 2017 at "Genes"

DOI: 10.3390/genes8060161

Abstract: Spinal muscular atrophy (SMA) is a genetic disorder with severity ranging from premature death in infants to restricted motor function in adult life. Despite the genetic cause of this disease being known for over twenty… read more here.

Keywords: spinal muscular; switching therapy; splice switching; muscular atrophy ... See more keywords

Expansion of Splice-Switching Therapy with Antisense Oligonucleotides

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recommendations! Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26052270

Abstract: Since 2016, splice-switching therapy, in which splicing is controlled by antisense oligonucleotides, has been applied in clinical practice for spinal muscular atrophy and Duchenne muscular dystrophy. In the former disease, this therapy induces exon inclusion,… read more here.

Keywords: therapy; splice switching; switching therapy; antisense oligonucleotides ... See more keywords