Neuroprotective effect of FMS-like tyrosine kinase-3 silence on cerebral ischemia/reperfusion injury in a SH-SY5Y cell line.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.01.043
Abstract: Neuron damage contributes to ischemic brain injury. Although FMS-like tyrosine kinase-3 (FLT3) plays a critical role in neuron survival, its function and molecular mechanism in cerebral ischemia/reperfusion injury is unclear. In the present study, we… read more here.
Keywords: sy5y cell; silence; sy5y; ischemia reperfusion ... See more keywords
Brain injury, genotoxic damage and oxidative stress induced by Bromuconazole in male Wistar rats and in SH-SY5Y cell line
Sign Up to like & getrecommendations! Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2087002
Abstract: Abstract Background Bromuconazole is a widely used triazole against various fungi disease. It’s employment provokes harmful effects on the environment and human health. In the present study, we explored bromuconazole toxic effects in both rat… read more here.
Keywords: sy5y cell; cell line; oxidative stress; brain ... See more keywords
α-synuclein accumulation in SH-SY5Y cell impairs autophagy in microglia by exosomes overloading miR-19a-3p.
Sign Up to like & getrecommendations! Published in 2019 at "Epigenomics"
DOI: 10.2217/epi-2019-0222
Abstract: Aims: To reveal whether miRNAs in exosomes from α-synuclein transgenic SH-SY5Y cells are able to regulate autophagy in recipient microglia. Materials & methods: Microarray analysis and experimental verification were adopted to assess the significance of… read more here.
Keywords: sy5y cell; transgenic sy5y; autophagy recipient; sy5y ... See more keywords