Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line: Quantitative Structure–Activity Relationship Models
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DOI: 10.1007/s00044-018-2245-2
Abstract: Chalcones are a group of molecules with a broad spectrum of biological activities, being especially appealing for their antiproliferative effects on several cancer cell lines. For this reason, we synthesized 23 chalcones with good to… read more here.
Keywords: sy5y neuroblastoma; cell line; cancer cell; cell ... See more keywords
Do 50/60 Hz magnetic fields influence oxidative or DNA damage responses in human SH-SY5Y neuroblastoma cells?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2022.2055803
Abstract: Abstract Purpose We investigated the possible effects of 50 and 60 Hz magnetic fields (MFs) on reactive oxygen species (ROS) production, DNA damage, DNA damage repair rate, as well as gene expression related to oxidative stress… read more here.
Keywords: sy5y neuroblastoma; damage; dna damage; human sy5y ... See more keywords
Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmz104
Abstract: The widely used inhalation anesthetic, isoflurane, potentially induces neuronal injury in clinical practice. Previous studies showed multiple forms of cell death that resulted from isoflurane-induced cytotoxicity, but the precise underlying mechanism remains poorly understood. Ferroptosis… read more here.
Keywords: sy5y neuroblastoma; ferroptosis; isoflurane induced; induced toxicity ... See more keywords
Novel synthetic lipopeptides derived from Mycoplasma hyorhinis upregulate calpastatin in SH-SY5Y neuroblastoma cells and induce a neuroprotective effect against amyloid-β-peptide toxicity.
Sign Up to like & getrecommendations! Published in 2020 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnaa073
Abstract: Previously we showed that contamination of SH-SY5Y neuroblastoma cells by Mycoplasma hyorhinis strains NDMh and MCLD leads to increased levels of calpastatin (the endogenous, specific inhibitor of the Ca2+-dependent protease calpain), resulting in inhibition of… read more here.
Keywords: sy5y neuroblastoma; neuroblastoma cells; mycoplasma hyorhinis; toxicity ... See more keywords
In Vitro Neurotoxicity of Flumethrin Pyrethroid on SH-SY5Y Neuroblastoma Cells: Apoptosis Associated with Oxidative Stress
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DOI: 10.3390/toxics10030131
Abstract: Pyrethroids are neurotoxicants for animals, showing a pattern of toxic action on the nervous system. Flumethrin, a synthetic pyrethroid, is used against ectoparasites in domestic animals, plants, and for public health. This compound has been… read more here.
Keywords: stress; sy5y neuroblastoma; oxidative stress; neuroblastoma cells ... See more keywords