A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006147
Abstract: Key Points HCK facilitates TLR/BCR crosstalk through activation of SYK in response to mutated MYD88. The HCK inhibitor A419259 selectively blocks SYK activation in MYD88 mutated cell lines and primary WM lymphoplasmacytic cells. read more here.
Keywords: hck; syk activation; myd88 mutated; activation myd88 ... See more keywords