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Published in 2017 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.1014
Abstract: SYM‐1219, a novel oral granule formulation of secnidazole, is under development as single‐dose treatment for bacterial vaginosis. This 4‐way, randomized, crossover study evaluated the effects of SYM‐1219 on electrocardiographic (ECG) parameters in 52 healthy subjects.…
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Keywords:
sym 1219;
qtc evaluation;
safety;
evaluation cardiac ... See more keywords
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Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.08.087
Abstract: administration with a meal or soft foods, and the impact of high doses of secnidazole on cardiac safety. SYM-1219 was administered in either applesauce, yogurt, or pudding, followed by 240 mL of water. Serial blood…
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Keywords:
protease inhibitor;
sym 1219;
metabolism;
sym ... See more keywords
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Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.08.088
Abstract: administration with a meal or soft foods, and the impact of high doses of secnidazole on cardiac safety. SYM-1219 was administered in either applesauce, yogurt, or pudding, followed by 240 mL of water. Serial blood…
read more here.
Keywords:
sym 1219;
patterns predictors;
metabolism;
predictors mode ... See more keywords