Using bispecific antibodies in forced degradation studies to analyze the structure–function relationships of symmetrically and asymmetrically modified antibodies
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DOI: 10.1080/19420862.2019.1618675
Abstract: ABSTRACT Forced degradation experiments of monoclonal antibodies (mAbs) aid in the identification of critical quality attributes (CQAs) by studying the impact of post-translational modifications (PTMs), such as oxidation, deamidation, glycation, and isomerization, on biological functions.… read more here.
Keywords: function; structure function; symmetrically asymmetrically; forced degradation ... See more keywords