The Pseudodystonia of Paroxysmal Sympathetic Hyperactivity: A Reversible Post‐Anoxic Complication
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13095
Abstract: A 28-year-old male developed episodes of tachycardia (150–170 beats per minute), fever (38.6 C), diaphoresis, tachypnea, and non-stereotypical episodes consistent of involuntary hip and foot flexion followed by arm flexion and neck extension 6 days… read more here.
Keywords: psh; hyperactivity; paroxysmal sympathetic; day ... See more keywords
Paroxysmal sympathetic hyperactivity risk modeling based on transients in time series describing the autonomic nervous system and cerebral hemodynamics
Sign Up to like & getrecommendations! Published in 2025 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-025-06566-9
Abstract: Overstimulation of the autonomic nervous system (ANS) in the acute phase after traumatic brain injury (TBI) may lead to paroxysmal sympathetic hyperactivity (PSH) syndrome. This study aimed to investigate the impact of the relationship between… read more here.
Keywords: cerebral hemodynamics; hemodynamics; sympathetic hyperactivity; paroxysmal sympathetic ... See more keywords
Spasticity management and resolution of paroxysmal sympathetic hyperactivity in the acute care setting: a case series
Sign Up to like & getrecommendations! Published in 2022 at "Brain Injury"
DOI: 10.1080/02699052.2022.2077441
Abstract: ABSTRACT Objective The aim is to highlight three cases of focal spasticity and/or dystonia as potential noxious triggers and treatment targets of Paroxysmal Sympathetic Hyperactivity (PSH). Methods We review the literature, explore pathophysiology, and review… read more here.
Keywords: spasticity; management; paroxysmal sympathetic; treatment ... See more keywords
Pharmacological management of Paroxysmal Sympathetic Hyperactivity (PSH): a scoping review.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neurotrauma"
DOI: 10.1089/neu.2020.7597
Abstract: Paroxysmal sympathetic hyperactivity (PSH) occurs in ~10% of patients following acute severe brain injury. Whilst PSH is associated with worse outcomes there are no clinical practice guidelines to inform treatment. We aimed to systematically review… read more here.
Keywords: psh; hyperactivity psh; case; management ... See more keywords
IMMU-09. REVERSING SYSTEMIC T CELL DYSFUNCTION TO LICENSE IMMUNOTHERAPY IN INTRACRANIAL TUMORS
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae165.0602
Abstract: Intracranial tumors present unique challenges for immunotherapy. These can include both local and systemic modes of immune suppression, the mechanistic underpinnings of which are incompletely understood. Our work reveals that intracranial tumors elicit systemic increases… read more here.
Keywords: sympathetic hyperactivity; cell dysfunction; immunotherapy intracranial; license immunotherapy ... See more keywords
Effect of oxidative stress in rostral ventrolateral medulla on sympathetic hyperactivity after traumatic brain injury
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14374
Abstract: Sympathetic hyperactivity occurs in a subgroup of patients after traumatic brain injury (TBI). The rostral ventrolateral medulla (RVLM) is a key region for the activity of sympathetic nervous system. Oxidative stress in the RVLM is… read more here.
Keywords: oxidative stress; stress; injury; rvlm ... See more keywords
New insights into the central sympathetic hyperactivity post‐myocardial infarction: Roles of METTL3‐mediated m6A methylation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17183
Abstract: Ventricular arrhythmias (VAs) triggers by sympathetic nerve hyperactivity contribute to sudden cardiac death in myocardial infarction (MI) patients. Microglia‐mediated inflammation in the paraventricular nucleus (PVN) is involved in sympathetic hyperactivity after MI. N6‐methyladenosine (m6A), the… read more here.
Keywords: mettl3 mediated; mediated m6a; myocardial infarction; hyperactivity ... See more keywords
Sepsis or sympathetics? Paroxysmal sympathetic hyperactivity after pontine stroke
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-236873
Abstract: A 64-year-old man from nursing home with a pontine stroke 3 months ago, ventilator-dependent, presented with episodic fever, tachycardia and tachypnoea occurring several times a day. He was evaluated for sepsis and pulmonary embolism and… read more here.
Keywords: sepsis; paroxysmal sympathetic; pontine stroke; sympathetic hyperactivity ... See more keywords
Dexmedetomidine attenuates acute paroxysmal sympathetic hyperactivity.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16920
Abstract: We evaluated the curative effect of dexmedetomidine on paroxysmal sympathetic hyperactivity (PSH) in a retrospective study of 72 PSH patients after neurosurgery. Our results showed that dexmedetomidine was superior to propofol for treatment of PSH… read more here.
Keywords: psh; paroxysmal sympathetic; dexmedetomidine; average time ... See more keywords
Paroxysmal Sympathetic Hyperactivity, Volume Status, and Neurological Prognosis in Acute Brain Injury: A Prospective Cohort Analysis
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s525766
Abstract: Objective In this study, we enrolled patients with acute brain injury (ABI) to examine the relationship between paroxysmal sympathetic hyperactivity (PSH) and volume status, right heart function, and pulmonary edema, and their impact on prognosis.… read more here.
Keywords: volume status; sympathetic hyperactivity; paroxysmal sympathetic;
Paroxysmal sympathetic hyperactivity and cerebral salt wasting post management of arteriovenous malformation in a pediatric patient: A case report
Sign Up to like & getrecommendations! Published in 2025 at "Surgical Neurology International"
DOI: 10.25259/sni_802_2024
Abstract: Background Spontaneous intracranial hemorrhage (ICH) is a rare presentation in healthy pediatric patients due to a myriad of conditions. Among them, arteriovenous malformations (AVMs) stand out for their potential to rupture and risk of death… read more here.
Keywords: sympathetic hyperactivity; paroxysmal sympathetic; post; cerebral salt ... See more keywords