G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.
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DOI: 10.1182/blood-2016-07-725754
Abstract: Granulocyte colony-stimulating factor (G-CSF) is widely used for peripheral blood stem/progenitor mobilization. G-CSF causes low-grade fever that is ameliorated by nonsteroidal anti-inflammatory drugs (NSAIDs), suggesting the activation of arachidonic acid (AA) cascade. How G-CSF regulated… read more here.
Keywords: sympathetic tone; csf induced; pge2; csf ... See more keywords