Identifying symptomatic adverse events using the patient‐reported outcomes version of the common terminology criteria for adverse events in patients with non‐small cell lung cancer with epidermal growth factor receptor exon 20 insertion mutations
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DOI: 10.1002/cam4.5376
Abstract: Tolerability and safety of treatments are important in oncology trials and should be informed by patient assessments. We identified the most relevant patient‐reported symptomatic adverse events (AEs) to measure in patients with non‐small cell lung… read more here.
Keywords: non small; patient reported; patients non; symptomatic adverse ... See more keywords
Commentary on King-Kallimanis et al.: Inadequate measurement of symptomatic adverse events in immunotherapy registration trials
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DOI: 10.1177/1740774519836989
Abstract: Symptomatic adverse events are common with cancer therapies, and provide key information about tolerability during development and regulatory review. After a therapy becomes available on the market, information about these adverse events is essential for… read more here.
Keywords: information; symptomatic adverse; adverse events; oncology ... See more keywords
Timing is everything: The importance of patient-reported outcome assessment frequency when characterizing symptomatic adverse events
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DOI: 10.1177/17407745221093935
Abstract: Objective Although patient-reported symptoms and side effects are increasingly measured in cancer clinical trials, an appropriate assessment frequency has not yet been established. To determine whether differences in assessment frequency affect the apparent incidence and… read more here.
Keywords: patient reported; reported outcome; patient; symptomatic adverse ... See more keywords
Lack of Concordance in Symptomatic Adverse Event Reporting by Children, Clinicians, and Caregivers: Implications for Cancer Clinical Trials
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DOI: 10.1200/jco.21.02669
Abstract: PURPOSE To examine concordance in symptomatic adverse event (AE) grading using the Common Terminology Criteria for Adverse Events (CTCAE 4.0) for clinicians and its patient-reported outcome (PRO) versions for children (Ped-PRO-CTCAE) and caregivers (Ped-PRO-CTCAE [Caregiver]).… read more here.
Keywords: clinicians caregivers; concordance; symptomatic adverse; adverse event ... See more keywords