Changes in symptoms of anhedonia in adults with major depressive or bipolar disorder receiving IV ketamine: Results from the Canadian Rapid Treatment Center of Excellence.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2020.07.083
Abstract: BACKGROUND Anhedonia is a trans-diagnostic, multidimensional phenotype that mediates patient outcomes and suicidality. Convergent evidence suggests that ketamine may be effective in targeting measures of anhedonia in adults with treatment resistant depression (TRD). METHODS This… read more here.
Keywords: symptoms anhedonia; depression; treatment; severity ... See more keywords
Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women.
Sign Up to like & getrecommendations! Published in 2020 at "Social cognitive and affective neuroscience"
DOI: 10.1093/scan/nsz100
Abstract: Trauma exposure is associated with increased inflammatory biomarkers (e.g. C-reactive protein [CRP] and cytokines), and inflammation has been shown to impact corticostriatal reward circuitry and increase anhedonia-related symptoms. We examined resting-state functional MRI in a… read more here.
Keywords: symptoms anhedonia; anhedonia ptsd; inflammation; trauma ... See more keywords