AAV2/DJ-mediated alpha-synuclein overexpression in the rat substantia nigra as early stage model of Parkinson’s disease
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DOI: 10.1007/s00441-019-03013-x
Abstract: Parkinson’s disease (PD) is pathologically characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and alpha-synucleinopathy. We mimic the disease pathology with overexpression of either the human α-syn… read more here.
Keywords: syn; disease; syn e46k; substantia nigra ... See more keywords