Novel SYN1 Variant in Two Brothers with Focal Epilepsy and Their Prompt Response to Valproate
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DOI: 10.1055/a-2019-0136
Abstract: Abstract Synapsins are neuron-specific phosphoproteins that modulate neurotransmitter release, synaptic plasticity, and molecular processes shaping higher brain functions. Pathogenic synapsin-1 ( SYN1 ) variants are associated with epilepsy, intellectual disabilities, and behavioral problems. We detected… read more here.
Keywords: syn1 variant; brothers focal; syn1; novel syn1 ... See more keywords
Selected prebiotics and synbiotics administered in ovo can modify innate immunity in chicken broilers
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DOI: 10.1186/s12917-019-1850-8
Abstract: BackgroundA previous study showed that prebiotics and synbiotics administered in ovo into the egg air cell on the 12th day of incubation enhance the growth and development of chickens. However, the influence of this procedure… read more here.
Keywords: syn1; synbiotics administered; prebiotics synbiotics; selected prebiotics ... See more keywords
In Vitro Neuroprotection of Rat Hippocampal Neurons by Manninotriose and Astragaloside IV Against Corticosterone-Induced Toxicity
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DOI: 10.3390/molecules23123339
Abstract: A chronically elevated glucocorticoid level impairs memory and cognition. Manninotriose is the main oligosaccharide of Prepared Radix Rehmanniae, and Astragaloside IV (AS-IV) is the primary ingredient of Astragali Radix; they have been reported to possess… read more here.
Keywords: hippocampal neurons; vitro neuroprotection; corticosterone; syn1 ... See more keywords