Presynaptic activity and protein turnover are correlated at the single-synapse level.
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DOI: 10.1016/j.celrep.2021.108841
Abstract: Synaptic transmission relies on the continual exocytosis and recycling of synaptic vesicles. Aged vesicle proteins are prevented from recycling and are eventually degraded. This implies that active synapses would lose vesicles and vesicle-associated proteins over… read more here.
Keywords: protein turnover; single synapse; turnover; synapse level ... See more keywords