Shank3 regulates striatal synaptic abundance of Cyld, a deubiquitinase specific for Lys63‐linked polyubiquitin chains
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DOI: 10.1111/jnc.14796
Abstract: The SH3 and multiple ankyrin repeat domains 3 (Shank3) proteins are core organizers of the postsynaptic density in neuronal excitatory synapses, and their defects cause various neurodevelopmental and neuropsychiatric disorders. Mechanistically, Shank3 directly and indirectly… read more here.
Keywords: synaptic abundance; lys63 linked; cyld; polyubiquitin chains ... See more keywords