Articles with "synaptic defects" as a keyword



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Ibrutinib alleviates LPS-induced neuroinflammation and synaptic defects in a mouse model of depression

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Published in 2021 at "Brain, Behavior, and Immunity"

DOI: 10.1016/j.bbi.2020.11.008

Abstract: Previous studies have demonstrated a close association between an altered immune system and major depressive disorders, and inhibition of neuroinflammation may represent an alternative mechanism to treat depression. Recently, the anti-inflammatory activity of ibrutinib has… read more here.

Keywords: depression; ibrutinib; lps induced; neuroinflammation ... See more keywords