A psychiatric disease-related circular RNA controls synaptic gene expression and cognition
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Psychiatry"
DOI: 10.1038/s41380-020-0653-4
Abstract: Although circular RNAs (circRNAs) are enriched in the mammalian brain, very little is known about their potential involvement in brain function and psychiatric disease. Here, we show that circHomer1a , a neuronal-enriched circRNA abundantly expressed… read more here.
Keywords: cortex; psychiatric disease; gene expression; disease ... See more keywords
The Synaptic Gene Study: Design and Methodology to Identify Neurocognitive Markers in Phelan-McDermid Syndrome and NRXN1 Deletions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.806990
Abstract: Synaptic gene conditions, i.e., “synaptopathies,” involve disruption to genes expressed at the synapse and account for between 0.5 and 2% of autism cases. They provide a unique entry point to understanding the molecular and biological… read more here.
Keywords: pms nrxn1ds; autism; methodology; synaptic gene ... See more keywords