Sleep, synaptic homeostasis and neuronal firing rates
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.03.016
Abstract: The synaptic homeostasis hypothesis (SHY) states that wake brings about a net overall increase in synaptic strength in many brain circuits that needs to be renormalized by sleep. I will review recent studies that were… read more here.
Keywords: firing rates; synaptic homeostasis; neuronal firing; firing ... See more keywords
Lead, cadmium, arsenic, and mercury combined exposure disrupted synaptic homeostasis through activating the Snk-SPAR pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.07.116
Abstract: Lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) are among the leading toxic agents detected in the environment, and they have also been detected simultaneously in blood, serum, and urine samples of the general… read more here.
Keywords: synaptic homeostasis; exposure; lead cadmium; cadmium arsenic ... See more keywords
Regulation and roles of mitophagy at synapses
Sign Up to like & getrecommendations! Published in 2020 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2020.111216
Abstract: Maintenance of synaptic homeostasis is a challenging task, due to the intricate spatial organization and intense activity of synapses. Typically, synapses are located far away from the neuronal cell body, where they orchestrate neuronal signalling… read more here.
Keywords: regulation roles; synaptic homeostasis; mitophagy synapses; roles mitophagy ... See more keywords
1374 Combined exposure to lead, cadmium, arsenic, and mercury alters synaptic homeostasis through snk-spar pathway in neuronal cells
Sign Up to like & getrecommendations! Published in 2018 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2018-icohabstracts.1436
Abstract: Introduction Lead, cadmium, arsenic, and mercury are widely used in industry and among the leading toxic agents detected in the environment. The deleterious effects encountered after exposure to these individual metals in low doses are… read more here.
Keywords: spar; snk spar; synaptic homeostasis; exposure ... See more keywords