Articles with "synaptic localisation" as a keyword



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Synaptic Localisation of Tau.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-32-9358-8_9

Abstract: The microtubule-associated protein tau has been identified in several intraneuronal compartments, including in association with synapses. In Alzheimer's disease, frontotemporal dementia and related tauopathies, highly phosphorylated tau accumulates as intraneuronal protein aggregates that are likely… read more here.

Keywords: tau; synaptic localisation; localisation; localisation tau ... See more keywords
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Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-18905-7

Abstract: The megakaryoblastic leukaemia (MKL) family are serum response factor (SRF) coactivators, which are highly expressed in the brain. Accordingly, MKL plays important roles in dendritic morphology, neuronal migration, and brain development. Further, nucleotide substitutions in… read more here.

Keywords: srf coactivators; synaptic localisation; dendritic spine; mkl1 mkl2 ... See more keywords