Bisphenol A Impairs Synaptic Plasticity by Both Pre‐ and Postsynaptic Mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Science"
DOI: 10.1002/advs.201600493
Abstract: Bisphenol A (BPA), an environmental xenoestrogen, has been reported to induce learning and memory impairments in rodent animals. However, effects of BPA exposure on synaptic plasticity and the underlying physiological mechanisms remain elusive. Our behavioral… read more here.
Keywords: bisphenol impairs; bpa exposure; synaptic plasticity; impairs synaptic ... See more keywords
Effects of platelet‐rich plasma on the memory impairment, apoptosis, and hippocampal synaptic plasticity in a rat model of hepatic encephalopathy
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2447
Abstract: In the present study, we aimed to determine whether intraperitoneal injection of platelet‐rich plasma (PRP) could have a neuroprotective effect on learning, memory, and synaptic plasticity impairment as well as hippocampal apoptosis in rats with… read more here.
Keywords: rich plasma; synaptic plasticity; platelet rich; memory ... See more keywords
An enriched environment improves maternal sleep deprivation-induced cognitive deficits and synaptic plasticity via hippocampal histone acetylation.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3018
Abstract: INTRODUCTION Growing evidence clearly demonstrates that maternal rodents exposure to sleep deprivation (SD) during late pregnancy impairs learning and memory in their offspring. Epigenetic mechanisms, particularly histone acetylation, are known to be involved in synaptic… read more here.
Keywords: memory; synaptic plasticity; acetylation; histone acetylation ... See more keywords
Microglia modulate TNFα-mediated synaptic plasticity.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24383
Abstract: The pro-inflammatory cytokine tumor necrosis factor α (TNFα) tunes the capacity of neurons to express synaptic plasticity. It remains, however, unclear how TNFα mediates synaptic positive (=change) and negative (=stability) feedback mechanisms. We assessed effects… read more here.
Keywords: tnf; mediated synaptic; plasticity; tnf mediated ... See more keywords
Astrocytic A2A receptors silencing negatively impacts hippocampal synaptic plasticity and memory of adult mice.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24384
Abstract: Astrocytes are wired to bidirectionally communicate with neurons namely with synapses, thus shaping synaptic plasticity, which in the hippocampus is considered to underlie learning and memory. Adenosine A2A receptors (A2A R) are a potential candidate… read more here.
Keywords: synaptic plasticity; plasticity memory; astrocytic a2a; plasticity ... See more keywords
Theta‐paced flickering between place‐cell maps in the hippocampus: A model based on short‐term synaptic plasticity
Sign Up to like & getrecommendations! Published in 2017 at "Hippocampus"
DOI: 10.1002/hipo.22743
Abstract: Hippocampal place cells represent different environments with distinct neural activity patterns. Following an abrupt switch between two familiar configurations of visual cues defining two environments, the hippocampal neural activity pattern switches almost immediately to the… read more here.
Keywords: term synaptic; model; place; synaptic plasticity ... See more keywords
Bidirectional regulation by “star forces”: Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23486
Abstract: The role of astrocytes in modulating synaptic plasticity is an important question that until recently was not addressed due to limitations of previously existing technology. In the present study, we took an advantage of optogenetics… read more here.
Keywords: opto a1ar; depression; basal; stimulation ... See more keywords
Choline chloride modulates learning, memory, and synaptic plasticity impairments in maternally separated adolescent male rats
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10155
Abstract: Maternal separation (MS) is a model to induce permanent alternations in the central nervous system (CNS) and is associated with increased levels of anxiety and cognitive deficiencies. Since methyl donor choline (Ch) has been shown… read more here.
Keywords: memory; synaptic plasticity; learning memory; choline chloride ... See more keywords
Effects of prenatal methamphetamine exposure on spatial cognition and hippocampal synaptic plasticity in adolescent rats
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10202
Abstract: Global rise in methamphetamine (MA) abuse during pregnancy has placed a large number of children at risk for the adverse consequences of prenatal methamphetamine exposure (PME). While behavioral and neurocognitive deficits of PME have been… read more here.
Keywords: pme; hippocampal synaptic; methamphetamine; synaptic plasticity ... See more keywords
Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-1370-7_9
Abstract: Aluminum, an environmentally abundant non-redox trivalent cation, has long been reported to alter blood-brain barrier and gets deposited in different regions of the brain. Many reports strongly indicated that Al had an adverse impact on… read more here.
Keywords: mechanism; variation synaptic; electrophysiological variation; synaptic plasticity ... See more keywords
Adolescent social instability stress alters markers of synaptic plasticity and dendritic structure in the medial amygdala and lateral septum in male rats
Sign Up to like & getrecommendations! Published in 2018 at "Brain Structure and Function"
DOI: 10.1007/s00429-018-1789-8
Abstract: Much evidence indicates that experiences in adolescence can alter the development of social behaviour. We previously demonstrated that male rats exposed to social instability stress in adolescence (SS; 1 h isolation and return to an unfamiliar… read more here.
Keywords: mea; stress; synaptic plasticity; markers synaptic ... See more keywords